Infectious Disease & Microbiome Models

Pathogen:
As a CRO, Pharmaseed is committed to assisting in the fight against various pathogens that cause high prevalence diseases, including MRSA, Influenza, Pneumonia, Covid 19 and others. Extensive experience gives our team an in-depth understanding of the complexities of Infectious diseases, expertise in feasibility assessment and site selection, protocol design, and establishment of an appropriate animal model in addition to those already established.

Microbiome:
Pharmaseed’s Bio-Safety Level 2 (BSL2) facilities enable us to conduct not only infectious diseases studies. Microbiome is a fast-growing field that is increasingly being associated with human health conditions. Manipulation of the human microbiome has shown therapeutic potential in cancer, inflammation, metabolic and neurological diseases.

Our services support an array of therapeutic disciplines

Cannabis based therapy

Microbiome

Pharmaceuticals

Medical devices

Biological therapy

Nutraceuticals

Cell & Gene based Therapy

Our Infectious Disease & Microbiome Models

Pathogen:

  • Infectious agent available: E.coli, Klebsiella, MRSA, Pseudomonas.
  • Species available: Mouse.
  • Standard assessments: Body weight, clinical signs, microbial burden determination (CFU), histology.
  • Additional assessments: Kidney function evaluation.
  • Model available: Cecal Ligation and Puncture (CLP).
  • Infectious agants available: E.coli, Klebsiella, MRSA, Pseudomonas.
  • Species available: Mouse, Rat.
  • Standard assessments: Body weight, clinical signs, survival.
  • Additional assessments: microbial burden determination (CFU).
  • Infectious agent available: Klebsiella, Pseudomonas.
  • Species available: Mouse.
  • Standard assessments: Body weight, clinical signs, survival, microbial burden determination (CFU), Histology.
  • Additional assessments: Upon request.
  • Models available: Bacteria induced IBD.
  • Species available: Mouse, Rat.
  • Standard assessments: Body weight, clinical signs, scoring, microbial burden determination (CFU), histology.
  • Additional assessments: Cytokine levels (ELISA), PCR.
  • Infectious agents available: E.coli, Klebsiella, Pseudomonas, Staphylococcus (including MRSA).
  • Species available: Mouse, Rat, Pig.
  • Standard assessments: Body weight, clinical signs, wound  closure measurement.
  • Additional assessments: Histology.

Microbiome:

  • Cancers available: Breast, Colon, Melanoma.
  • Species available: Mouse.
  • Standard assessments: Body weight, clinical signs, tumor measurement, microbial burden determination (CFU), PCR.
  • Additional assessments: Histology, tumor markers (ELISA, immunostaining).
  • Infectious agent available: Influenza, Covid19.
  • Species available: Mouse.
  • Standard assessments: Body weight, clinical signs, survival.
  • Additional assessments: Blood chemistry and biochemistry, cytokine levels (ELISA).

Additional clinical indications related to microbiome see:

Research outcomes - examples

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