Pharmaseed have extensive experience in evaluating anti-cancer drugs or therapies in order to show highly effective, and sometimes even spectacular anti-cancer treatment results using transplantable tumors in mice. These models involve human tumor xenografts grown subcutaneously in immune deficient hosts such as athymic (nude) or severe combined immune deficient (SCID) mice.
Multiple cancer models are available such as:
- Colon
- Breast
- Melanoma
- Liver
- Lung
- Pancreas
Anti-angiogenesis activity in solid xenogratft model
EMT6/CTX tumor cells were injected SC, 14 days post inoculation. tumor angiogenesis was assessed using Laser Doppler blood flow measurement for treated and unrelated mice.