Bloodebrain barrier permeability and tPA–mediated neurotoxicity

Neuropharmacology 58 (2010) 972e980

Rami Abu Fanne a,1, Taher Nassar b,1, Sergei Yarovoi b, Anwar Rayan c, Itschak Lamensdorf d, Michael Karakoveski e, Polianski Vadim e, Mahmud Jammal a, Douglas B. Cines b, Abd Al-Roof Higazi a,b,*

a Department of Clinical Biochemistry, Hebrew University – Hadassah Medical Center, Jerusalem, Israel

b Department of Pathology and Laboratory Medicine, University of Pennsylvania, 513A Stellar-Chance, 422 Curie Boulevard, Philadelphia, PA 19104, USA

c QRC-Qasemi Research Center, Baka El-Garbiah, Israel

d Thrombotech Ltd, Ness Ziona, Israel

e PharmaSeed Ltd, Ness Ziona, Israel

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